As a cat owner, your top priority is the health and comfort of your feline companion. Unfortunately, parasites like fleas, ticks, and ear mites pose a constant threat, causing everything from mild irritation to serious health complications. Nexgard® COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is a leading prescription medication designed to offer broad-spectrum protection. This comprehensive guide will explain how Nexgard for Cats works, break down the factors that influence its price, and provide actionable tips to help you get the best value while keeping your cat safe.

What is Nexgard for Cats & How Does It Work?

Nexgard for Cats is a monthly, prescription-only topical solution that provides comprehensive parasite protection. It’s not just for fleas and ticks; it’s a “combo” product that targets a wide array of internal and external parasites. This all-in-one treatment is formulated to prevent heartworm disease and treat and control fleas, ticks, ear mites, roundworms, and hookworms.

The effectiveness of Nexgard for Cats comes from its three active ingredients:

• Esafoxolaner: This ingredient is an ectoparasiticide, meaning it targets external parasites. It works by interfering with the nervous system of fleas and ticks, causing uncontrolled nerve activity and rapid death. According to the manufacturer, Boehringer Ingelheim Animal Health, it starts killing fleas within just six hours of application (Nexgard Clinic). It is specifically effective against the black-legged tick (Ixodes scapularis), which is a known carrier of Lyme disease.
• Eprinomectin: This ingredient targets internal parasites, known as endoparasites. It is highly effective in treating and controlling common intestinal worms like hookworms and roundworms.
• Praziquantel: This is another powerful dewormer that specifically targets tapeworms, which cats can contract from ingesting infected fleas.

This powerful combination is applied topically to the skin at the base of your cat’s neck once a month. It provides a full 30 days of protection, making it a convenient and effective way to ensure your cat remains free from a host of dangerous pests. For more comprehensive information on parasite prevention, you can review our complete guide to flea prevention.

Decoding the Cost of Nexgard for Cats

The price of Nexgard for Cats is not a single, fixed number; it varies based on several key factors. Understanding these variables will help you budget for your cat’s care and find the most cost-effective options. It is crucial to remember that as a prescription medication, you must have authorization from a licensed veterinarian to purchase it.

Here are the primary factors that influence the cost:

• Weight-Based Dosage: Nexgard for Cats comes in two different dosage strengths based on your cat’s weight. The pricing will differ between the product for cats weighing 1.8-5.5 lbs and the one for cats weighing 5.6-16.5 lbs. Larger cats require a higher dose of the active ingredients, which typically results in a slightly higher price.
• Package Size: The medication is most commonly sold in 3-dose and 6-dose packages. While a 6-dose package has a higher upfront cost, the price per individual applicator is almost always lower than buying a 3-dose pack. Purchasing in larger quantities is a reliable way to save money over time.
• Retailer Markup: Where you buy the medication is one of the biggest price determinants. A private veterinary clinic, a large retail pet store with a pharmacy, and an online pet pharmacy will all have different pricing structures. Online retailers like Chewy often have very competitive pricing due to lower overhead, with a 3-dose pack typically ranging from $70 to $85, depending on the dosage (Chewy.com).
• Geographic Location: The cost of veterinary products and services can fluctuate based on your city and state. Operating costs for businesses in metropolitan areas are often higher, which can be reflected in their pricing.

Where Can You Buy Nexgard for Cats?

Since Nexgard for Cats requires a prescription, you cannot simply pick it up off any shelf. You have several options for purchasing it, each with its own advantages and disadvantages.

1. Your Veterinarian’s Office:

• Pros: This is the most direct and often most convenient method. Your vet can provide the prescription and dispense the product in a single visit. You can also ask questions and receive immediate, professional advice.
• Cons: Prices at a local vet clinic may be higher than at online or large-scale retailers. Their inventory may also be limited to specific package sizes.

2. Online Pet Pharmacies:

• Pros: Reputable online pharmacies, such as Chewy, PetMeds, and others, frequently offer the most competitive pricing. They also provide the convenience of home delivery and often have auto-ship options that come with an additional discount.
• Cons: You will need to provide them with a valid prescription from your vet, which they will verify. You must also account for shipping time, so it’s important to order before your cat’s next dose is due.

3. Large Retail Stores with Pharmacies:

• Pros: Stores like Petco and PetSmart often have in-house veterinary clinics, allowing you to get an exam, a prescription, and the medication all in one place. Their pricing can sometimes be more competitive than that of a private clinic.
• Cons: Clinic hours and appointment availability can be limited. Their prices may still be higher than those found at dedicated online pharmacies. For instance, Petco’s listed price for a 3-dose pack is often in the $80-$95 range, subject to location and promotions (Petco).

Before purchasing, it is vital to know the warning signs of health issues in your pet. Our article on cat health warning signs can help you stay informed.

Smart Savings: How to Get the Best Price on Nexgard

Protecting your cat shouldn’t break the bank. With a little planning, you can significantly reduce the annual cost of parasite prevention. Here are some of the most effective strategies for saving money on Nexgard for Cats:

• Look for Manufacturer Rebates: The manufacturer, Boehringer Ingelheim, frequently offers rebates on its products. These promotions can provide substantial savings, especially when you purchase a 6-dose or 12-month supply. Check the official Nexgard website or ask your veterinarian about current offers.
• Sign Up for Auto-Ship Programs: Nearly all online pet pharmacies offer a discount for enrolling in their auto-ship or subscription service. This not only saves you money on each order (typically 5-10%) but also ensures you never forget to reorder and risk a lapse in your cat’s protection.
• Buy in Bulk: As mentioned, purchasing a 6-dose package is more economical per dose than a 3-dose package. If your budget allows for the higher initial cost, this is one of the easiest ways to save money over the course of six months.
• Compare Prices Across Retailers: Don’t buy from the first place you look. Take a few minutes to compare the price of your cat’s specific dosage on several websites, such as Chewy and PetMeds, and then compare those prices to what your local vet or Petco offers. Remember to factor in shipping costs or membership fees.
• Ask Your Vet About Promotions: Veterinarian offices sometimes receive exclusive promotions or sample doses from manufacturers. It never hurts to ask if they have any ongoing deals or if a different but equally effective product might be more affordable for your situation.

By using these strategies, you can make responsible pet ownership more affordable while providing your cat with the gold-standard protection they deserve.